What is the most populous U.S. city that was named for a President?
Founded in 1822, Jacksonville, Florida, was named for the first military governor of the Florida Territory, Andrew Jackson. Jackson went on to become the seventh U.S. president, serving from 1829 to 1837, but ironically he never actually set foot in the town that bears his name. Since then, Jacksonville has grown to a current population of more than 840,000 people.
Source: Visit Jacksonville